Every tumor is unique. In a new study, scientists from Zurich and Basel used advanced technologies to create individual profiles for precise tumor treatment.
AI has the ability to advance precision cancer treatment by using data to predict the course of the disease with greater accuracy. This saves resources and precious time.
A new study has shown that evidence of genetic susceptibility to schizophrenia can be found in the retina. This finding could help improve the early detection of the disorder.
Defects in the immune system are caused by antibodies that inhibit important defense proteins. UZH researchers have now generated "decoy molecules" that can intercept these autoantibodies.
The symptoms of schizophrenia vary greatly from person to person. A new study shows how these differences manifest themselves in the structure of the brain.
Curbing the Global Spread of Sexually Transmitted Diseases
Cases of bacterial sexually transmitted infections are on the rise worldwide. The University of Zurich has now developed a new method for genome sequencing and discovered a previously unrecognized strain of chlamydia
Onur Boyman became a doctor because he wanted to help people. Now, having achieved a breakthrough with his research on autoimmune diseases, the UZH professor plans to bring a new therapy to market – and switch role from head of clinic to entrepreneur.
The CRISPR tool is capable of repairing the genetic defect responsible for chronic granulomatous disease. However, UZH researchers have now shown that there is a risk of inadvertently introducing other defects.
"We need to intensify research into sepsis and coordinate it better"
Sepsis is a life-threatening disease which affects all age groups, but especially children. Luregn Schlapbach, professor of pediatric intensive care medicine, explains how both diagnosis and treatment of the disease could be improved.
Key Driver for Epithelial Cancer Development Identified
A distinct signaling pathway called TNF-α drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF-α program and become invasive - they spread into other organs.
In a few years, we’re likely to see personalized stem cells being used in the first clinical trials for heart patients. But there are still a few hurdles to overcome on the way from the lab to the clinic.
UZH and USZ researchers have further developed a new blood test to analyze liquid biopsies of DNA fragments in the blood. The new method is fast and practical, without putting much of a strain on patients – and might help to treat cancer patients more individually in the future.
The Mechanism Behind Melanoma Resistance to Treatment
In many cases of malignant melanoma, the effect of targeted treatment is lost over time. A research team from UZH and USZ has now discovered that a factor secreted by tumor cells is responsible for the resistance.
The heart is our most vital organ. But the heart muscle cells are sluggish. The cardiologist Carolin Lerchenmüller is exploring how these cells are regenerated and how the heart can be strengthened and protected.
“The tumor microenvironment enormously affects cancer cells”
One major achievement of the URPP Translational Cancer Research is the newly created “dialogue among equals between basic research and clinical practice,” sums up co-director Maries van den Broek.
UZH to Create Chair of Allergology and Asthma in Davos
The Swiss Institute of Allergy and Asthma Research (SIAF) in Davos is to be significantly strengthened with the creation of a Chair of Allergology and Asthma. An agreement on this was announced on 21 June 2024 by representatives of the Graubünden government and the UZH.
For many years, the male mouse was thought to be the measure of all things in pre-clinical research. Over time, scientists have come to realize that it is medically necessary to work with experimental animals of both sexes.